Frequently Asked Questions

Q: How do I use Progestelle?

A: Rub Progestelle on your skin once or twice per day.  Before bedtime is a good time put Progestelle on the skin.  Make sure to rotate sites.  If you keep doing right arm, right arm, right arm day after day, then the subcutaneous fat will saturate and the right arm will not be able to absorb any more progesterone.


Q: How much Progestelle do I use?

A: Each dropperful filled with oil measuring about 2 inches from the bottom of the dropper to the top of the dropper contains about 20 mg of Natural Progesterone.  The normal topical dosage for a woman is 20-60 mg/day.  You may use 1 to 3 dropperfuls per day of Progestelle.  Each drop of Progestelle contains 0.6 mg of Natural Progesterone.

At 20 mg/day used for 3 weeks out of 4 weeks, one bottle lasts 2 months.  At 60 mg/day, one bottle of Progestelle lasts 2 weeks.


Q: When should I use Progestelle?

A: Usually, women use progesterone from days 14-26 days where day 1 is the first day of their period for premenopausal women.  For post menopausal women, women use Progestelle 3 weeks out of 4 weeks.


Q: Does Progesterone work for everyone?

A: Usually, something good happens when taking progesterone.  However, progesterone does not work for everyone.  When progesterone does NOT work, the progesterone is interacting with something else that is being put on the skin.



Q: Why is the topical dose of Natural Progesterone Cream or Oil 20 mg/day while the equivalent dose of oral Natural Progesterone is 200 mg/day?

A: Topical transdermal Natural Progesterone Cream or Oil goes through the skin and goes directly into the body.  Oral Natural Progesterone in pill form is 90% first pass metabolized through the liver.  Thus, only 10% of oral Natural Progesterone goes into the body.  Thus, a transdermal topical progesterone dose of 20 mg is the same as an oral 200 mg dose.


Q: Why is my blood hormone progesterone test show ZERO after taking topical transdermal Natural Progesterone Cream or Oil?

A: Topical transdermal progesterone does NOT show up on the blood hormone test.  A saliva hormone test must be used instead.  This is because oil and water do NOT mix.

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